Medical technology

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Masimo SedLine for Improved Brain Monitoring Under Anesthesia FDA Cleared
Masimo won FDA clearance for its Next Generation SedLine brain function monitoring, a system for assessing the brain while under anesthesia. Next Generation SedLine relies on four EEG (electroencephalography) leads that acquire brain signals from both sides of the brain. The new version of the offering includes an improved signal processing engine that can help anesthesiologists have a better idea of what’s going on inside the cranium. The new engine produces a newly tuned Patient State Index (PSi) the readings from which can be easily integrated into a physician’s decision making process.
The product also produces Multitaper Density Spectral Array (DSA), an indicator created by Dr. Emery Brown, MD, PhD, and Dr. Patrick Purdon, PhD of the Neuroscience Statistics Research Lab at Massachusetts General Hospital. This indicator converts EEG readings into the frequency domain, providing a different look at the brain data and making it easier to understand.
The readings obtained with the Next Generation SedLine can be gathered at the same time along with  O3 regional oximetry, helping to assess cerebral oxygenation, on Masimo’s Root patient monitoring system.

GE Healthcare is unveiling a new budget conscious ultrasound system, the Versana Essential. GE touts it as having excellent image quality for the price and sees it being used by OB-GYNs, family and general practice physicians, and by clinicians in a number of other specialties. Using it you can view the thyroid vasculature, kidney vessels, and assess blood flow through the aorta, carotid, and other vessels. The Versana Essential has a number of semi-automated features that help to produce high resolution images and move scans forward, such as Whizz one-touch.dynamic image optimization, Auto IMT measurement, and SonoBiometry for fetal measurements. It does include Doppler capabilities.
For those getting acquainted with the device, GE Healthcare offers online tools called Scan Coach and My Trainer that help to learn how to use it properly...

Deep Brain Stimulation Shown Effective at Slowing Down Alzheimer’s Symptoms

At Ohio State University, clinical researchers have successfully tested deep brain stimulation as a possible treatment option to slow down the onset of Alzheimer's symptoms. Three patients with the disease had a Medtronic deep brain stimulator implanted, with leads reaching into the frontal lobe where a lot of advanced cognitive tasks are done. Following initiation of therapy, the researchers monitored the three patients for over three years, gauging their cognitive abilities throughout. Amazingly, all of the patients' cognitive decline was markedly slowed as compared to typical Alzheimer's patients. Here's a
summary of the findings of the study from the abstract in Journal of Alzheimer’s Disease:
AD participants given DBS for at least 18 months at the VC/VS target were compared on the Clinical Dementia Rating–Sum of Boxes (CDR-SB), our primary outcome clinical measure, to matched groups without DBS from the AD Neuroimaging Initiative (ADNI) cohort. Serial 2-Deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography (PET) images of AD participants were also compared longitudinally over time. Three AD DBS participants were matched to subjects from the ADNI cohort. All participants tolerated DBS well without significant adverse events. All three AD DBS participants had less performance decline and two of them meaningfully less decline over time on our primary outcome measure, CDR-SB, relative to matched comparison groups from the ADNI using score trajectory slopes. Minimal changes or increased metabolism on FDG-PET were seen in frontal cortical regions after chronic DBS at the VC/VS target. The first use of DBS in AD at a frontal lobe behavior regulation target (VC/VS) was well-tolerated and revealed less performance decline in CDR-SB



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